Background: A few studies have reported that mental health among People Living with HIV positive (PLHIV) is an important matter to be discussed. Therefore, there is evidence to support further research into exploration of mental health especially psychological intervention. This study will examine whether a psychological intervention (Cognitive Behaviour Therapy) could reduce depression, anxiety, and negative automatic thought in PLHIV. Methods: This proposed research study will adopt a cross-sectional and single-blind randomized controlled trial (RCT) design, conducted in two phases. In phase 1, participants will answer questionnaire that cover demographic, anxiety, depression, automatic thought, emotion regulation, stigma, adherence, and social support. Participants with high score in anxiety and depression automatically offered to be phase 2 participants, which is Randomized Controlled Trial (RCT). Anxiety, depression, and automatic thought score will be obtained before, immediately after and at 1-month follow-up after completing CBT. Discussion: This study aims to evaluate the effectiveness of a Cognitive Behavioral Therapy (CBT) program in reducing anxiety, depression, and negative automatic thoughts among people living with HIV (PLHIV). Additionally, it will examine the prevalence of anxiety and depression as well as the relationships between these variables. If the intervention proves effective, it could serve as a valuable mental health strategy and an alternative treatment option for PLHIV in Malaysia.
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